We improve crops with minimal changes

Phytoform utilises a proprietary predictive biology approach called CRE.AI.TIVE™ to redesign and prove novel patterns of gene activity for target genes.

We use an industry leading sequence-to-expression modelling algorithm, to predict gene activity across tissues and conditions. Together with simulated mutations, we create large promoter libraries to achieve novel gene expression patterns. We screen and validate these libraries with high-throughput expression testing in plant cells.

The outcomes are fine-tuned promoter variants that enable native and tissue/condition/temporal-specific overexpression. This allows us to modulate gene activity and to provide novel functional native traits.

Our priority is leveraging the power of native plant genetics to offer differentiated benefits focused on net-yield boosts, climate resilience and other traits contributing to food security. We design, test and implement valuable mutations directly into our partner’s germplasm. We achieve this with our proven footprint-free protoplast based CRISPR-Cas genome editing technology. We are translating science to impact, by delivering game-changing alleles without linkage drag into a wide range of commercial, elite varieties.

Our team specialises in development of robust and scalable protoplast-based transformation protocols built for compliance with emerging precision breeding rules and regulations around the globe.