We are looking for a motivated team member to work on Phytoform Labs core CRISPR-genome editing technology. You’ll be developing and improving methods for introducing and detecting precise genome edits in plants. You will be part of the Phytoform R&D team and will be interacting closely with our implementation team to make sure your R&D efforts are efficiently deployed in our crop breeding programs. If you have previously been part of an academic or industry team but now would like to work in a fast-paced start-up environment and develop a project from the ground up then you would be a great fit.
What You'll do
- Develop and improve CRISPR-mediated HDR methods to diversify edits in plants
- Perform a range of molecular tasks such as DNA and RNA isolation from plant material
- Prepare Next Generation Sequencing (NGS) sequencing libraries (Illumina, Oxford Nanopore)
- Design and execute bioinformatics pipelines for NGS data analysis and train other scientists in NGS workflows
- Work with RNPs and plasmids in transient protoplast transfection as part of the team
- Keep a well-organised record of all data and results electronically.
- Present and discuss your strategies and advancements to your manager and team.
Essential Requirements
- PhD or MSc + 4 years work experience in a relevant field such as Genomics, Molecular Biology, Biochemistry or similar
- Practical experience in genome editing technology and detection
- Expertise in molecular biology, including working with NGS libraries
- Experienced with loading and operating sequencing platforms, including Illumina (e.g., MiSeq, NextSeq, NovaSeq) and Oxford Nanopore (e.g., MinION, GridION)
- Competence in running and writing bioinformatic pipelines and analysing NGS or omics data (e.g. programming in Python, R or similar)
- Advanced problem solving within molecular biology with demonstrated success
- Strong communication and collaboration skills
- Track record of application driven research
- Goal focused and with good time management and excellent record keeping
- Ability to work in a results-driven, deadline-oriented team
- Share our passion for sustainability and vision of a future where genetic engineering
plays a key role in improving the resilience of global food systems
Beneficial Requirements
- Experience with CRISPR genome editing in plant species
- Experience working with plant protoplasts
- Practical experience with high throughput methods, such as FACS and high throughput imaging
What We Offer
- Competitive salary
- Share of the value you create through the Employee Stock Option Plan
- Private medical insurance
- Great working environment in a multidisciplinary team
- A flexible working arrangement: early or late working with core hours of 10am-4pm
- Possibility of working from home when compiling and analysing data
- Access to a gym & tennis courts
- Cycle to work scheme
If you’re looking for a new challenge and enjoy working as part of a small, multidisciplinary team where new ideas are welcomed, then we would love to meet you!
Application instructions
To apply, please submit a CV highlighting relevant experience and a cover letter (max 1 page) addressing your fit for the role and motivation to join the project in a single PDF file to apply@phytoformlabs.com stating “Senior Scientist – Plant CRISPR R&D” in the title.
Alternatively, apply through the Phytoform careers page https://www.phytoformlabs.com/careers.
Location: Harpenden, London, United Kingdom
Contract: Full-time, 3 years to 31st May 2028 (renewable based on project milestones and funding)
Visa status: Visa sponsorship can be considered for this position
Start Date: As soon as possible
Application Deadline: June 2025
Interviews: Rolling basis
Salary: compensation will be based on experience and qualifications + Stock Options
This job is part of an Advanced Research + Innovation Agency - funded project, subject to contract negotiations.
